This paper is to report the polymorphism of raw materials of clopidogrel bisulfate at home and abroad.  By the analysis of Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (p-XRD), samples are roughly classified into two groups, except one patent material.  And the differential scanning calorimeter (DSC) examination showed more detailed information for these materials.  The results of the study could provide comprehensive basis for the quality evaluation of clopidogrel bisulfate.