抗高血压药物2-亚氨基-3-(β-羟基苯乙基)-噻唑烷衍生物的合成
ANTIHYPERTENSIVE COMPOUNDS SYNTHESIS OF 2-1MINO-3-(β-HYDROXYPHENETHYL) THIAZOLIDINE DERIVATIVES
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Abstract: 2-Imino-3-(β-hydroxyphenethyl)thiazolidine showed hypotensive activity. In order to find more active derivatives, a series of compounds has been synthesized.In preliminary screening tests, Compounds (Ⅱ-2) and (Ⅳ-1) showed considerable hypotensive effect.
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