胡芦巴皂苷VIII的结构鉴定

STRUCTURAL IDENTIFICATION OF TRIGONEOSIDE VIII

摘要: 目的　研究中国产胡芦巴Trigonellafoenum graecumL .种子的化学成分。方法　采用硅胶色谱柱进行分离,通过物理、化学和光谱学方法鉴定化合物的结构。结果　分离得到一甾体皂苷,命名为胡芦巴皂苷VIII,鉴定其结构为26-O-β-D-吡喃葡糖基-25(R)-5α-呋甾烷-20(22)-烯-2α,3β,26-三醇-3-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡糖苷。结论　胡芦巴皂苷VIII为新化合物。

Abstract: AIM To study the chemical constituents of the seeds of Trigonella foenum-graecum (fenugreek). METHODS The compound was isolated with silica gel chromatography and its structure was identified by physical, chemical properties and spectral analysis. RESULTS A furostanol saponin named trigoneoside VIII has been isolated from the ethanol extract of the seeds of Trigonella foenum-graecum. Its structure has been determined as 26-O-β-D-glucopyranosyl-25(R)-5α-furostan-20(22)-en-2α,3β,26-triol-3-O-β-D-xylopyranosyl (1→6)-β-D-glucopyranoside. CONCLUSION Trigoneoside VIII is a new compound.