颜闵, 张振, 雷兴翰, 席裕瑞, 徐裕信. 丝虫病化学治疗的研究 Ⅲ.5-硝基-2-噻吩甲亚胺和3,5-二硝基-2-噻吩胺衍生物的合成J. 药学学报, 1985, 20(3): 219-223.
引用本文: 颜闵, 张振, 雷兴翰, 席裕瑞, 徐裕信. 丝虫病化学治疗的研究 Ⅲ.5-硝基-2-噻吩甲亚胺和3,5-二硝基-2-噻吩胺衍生物的合成J. 药学学报, 1985, 20(3): 219-223.
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YAN Min, ZHANG Zhen, LEI Xing-Han, XI Yu-Rui , XU Yu-Xin, . STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVESJ. Acta Pharmaceutica Sinica, 1985, 20(3): 219-223.
Citation: YAN Min, ZHANG Zhen, LEI Xing-Han, XI Yu-Rui , XU Yu-Xin, . STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVESJ. Acta Pharmaceutica Sinica, 1985, 20(3): 219-223.
shu

丝虫病化学治疗的研究 Ⅲ.5-硝基-2-噻吩甲亚胺和3,5-二硝基-2-噻吩胺衍生物的合成

STUDIES ON CHEMOTHERAPY OF FILARIASIS Ⅲ. SYNTHESIS OF 5-NITRO-2-THIENYLAZOMETHINE AND 3, 5-DINI-TRO-2-THIENYLAMINE DERIVATIVES

    摘要
  • Abstract: In order to improve the clinical efficacy of the new oral filaricide, Furapyrimidone, a number of 5-nitro-2-thienylazomethine and 3,5-dinitro-2-thicnylamine derivatives were synthesized. After screening, twenty-one out of thirty-two compounds were found to possess pronounced macrofilaricidal effect.

     

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