异叶梁王茶甙Ⅲ和Ⅳ的结构

THE STRUCTURES OF YIYELIANGWANOSIDE Ⅲ AND Ⅳ FROM THE BARK OF NOTHOPANAX DAVIDⅡ(FRANCE) HARMS

摘要: 继前报后,又从异叶梁王茶Nothopanax davidii(France)Harms树皮中分离得到两种五环三萜皂甙。经化学和波谱(IR,¹HNMR,~(13)CHMR,¹H-¹HCOSY,¹³C-¹H COSY,MS)分析,分别鉴定为3-O-α-(2’,4’-O-二乙酰基)-L-吡喃阿拉伯糖-3β-羟基齐墩果-12-烯-28,29-双羧酸-28-O-α-L-吡喃鼠李糖(1-4)-β-D-吡喃葡萄糖(1—6)-β-D-吡喃葡萄糖酯甙(Ⅲ),命名为异叶梁王茶甙Ⅲ和3-O-β-(2-O-乙酰基)-D-吡喃木糖-3β-羟齐墩果-12-烯-28,29-双羧酸甙(Ⅳ),命名为异叶梁王茶甙Ⅳ。这两种皂甙均系首次从植物中分出的新化合物。

Abstract: Two new oleanane type triterpene glycosides, named YiyeliangwanosideIII and IV, were isolated from Nothopanax davidii (France)Harms (Araliaceae).Their chemi-cal structures were elucidated by means of chemical and spectrometric analysis .Yiyeliangwanoside III: C₅₇H₈₈O₂₅, a white powder, mp 206～210℃(dec.), α_D+2.73 (c 0.1, CH₃OH). Its structure was determined as 3-O-α(2',4'- O-diacetyl)- L- arabinopyranosyl - 3β- hydroxyolean- 12 -ene- 28,29 - dioicacid - 28 - O - α-L- rhamnopyranosyl - (1 - 4 )-β- D- glucopyranosyl -(1-6 )-β-D-glucopyranosylester. Yiyeliangwanoside IV: C₃₇H₅₆O₁₀, a white powder, mp 267～170℃ (dec.), α_D²⁰+ 31.55°(c 0.1, CH₃OH ).Its structure was determined as 3 -O-α-(2'-O-acetyl )-D-xylopyranosyl-3β-hydroxyolean-12-ene-28,29-dioic acid.