广西九里香化学成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF MURRAYA KWANGSIENSIS

摘要: 目的　对广西九里香(Murraya kwangsiensis)的化学成分进行研究。方法　利用硅胶柱色谱和薄层色谱方法对广西九里香的95%乙醇提取物进行分离；采用UV,IR,MS,¹HNMR和¹³CNMR等技术对所得化合物进行结构研究。结果　分离鉴定了7个化合物，其中5个为咔巴唑生物碱:murrayafoline-A,murrayanine,koenine,isomahanine和广西九里香碱(kwangsine),两个非生物碱化合物：棕榈酸和β-谷甾醇。结论　广西九里香碱(kwangsine)为新化合物，其他化合物均为首次从该植物中分离得到。

Abstract: AIM　To investigate the chemical constituents of Murraya kwangsiensis. METHODS　Compounds were isolated by silica gel column chromatography and TLC method, respectively. Structures of compounds were elucidated by spectral (UV, IR, MS, ¹HNMR and ¹³CNMR) analysis. RESULTS　Five carbazole alkaloids and two other compounds were isolated and identified. Six of them are known compounds: murrayafoline A, murrayanine, koenine, isomahanine, palmitic acid and β-sitosterol. One is a new alkaloid, named kwangsine. CONCLUSION　A new alkaloid, named kwangsine, was isolated from Murraya kwangsiensis Var. Six known compounds were isolated from this plant for the first time.