灯心草酚性成分的分离与结构鉴定

Isolation and identification of phenolic constituents from Juncus effusus

摘要: 为研究灯心草科灯心草属植物灯心草(Juncus effusus L.)干燥茎髓中的酚性成分，运用正相和反相硅胶柱色谱法对灯心草乙酸乙酯部位进行分离纯化，并用波谱技术鉴定化合物结构。共分离得到6个酚性成分，其结构分别鉴定为7-羧基-2-羟基-1-甲基-5-乙烯基-9,10-二氢菲(1)，2,3-异丙叉-1-O-阿魏酰甘油酯(2)，(2S)-2,3-异丙叉-1-O-对羟基桂皮酰甘油酯(3)，dehydroeffusal(4)，对羟基苯甲醛(5)和毛地黄黄酮-5,3′-二甲酯(6)。其中化合物1和2为新化合物，化合物5和6为首次从该属植物中分得，本文首次报道了化合物6的¹³C NMR数据。

Abstract: To study the phenolic constituents from the dry stem of Juncus effusus L., the constituents were isolated by normal-phase and reverse-phase silica gel column chromatography from the EtOAc extract. Their structures were elucidated by spectral analysis. Six phenolic constituents were purified and identified as 7-carboxy-2-hydroxy-1-methyl-5-vinyl-9,10-dihydrophenanthrene (1), 2,3-isopylidene-1-O-ferulic acid glyceride (2), (2S)-2,3-isopylidene-1-O-p-coumaroyl glyceride (3), dehydroeffusal (4), P-hydroxybenzaldehyde (5) and luteolin-5,3′-dimethyl ether (6). Compounds 1 and 2 are new compounds. Compounds 5 and 6 were isolated from Juncaceae plant for the first time. ¹³C NMR data of compound 6 were reported for the first time.