金翼黄芪甙A的化学结构和绵毛黄芪甙ⅩⅤ及7,2′-二羟基-3′,4′二甲氧基异黄烷-7-O-β-D-葡萄糖甙二维核磁共振谱的研究

THE STRUCTURE OF ASTRACHRYSOSID A AND THE STUDY OF 2D-NMR ON ASTRASIEVERSIANIN XV AND 7, 2'-DIHYDROXY-3',4'-DIMETHOXY- ISOFLAVANE-7-O-β-D-GLYCOSIDE

摘要: 从金翼黄芪中分离出金翼黄芪甙A(Ⅰ),绵毛黄芪甙XV (Ⅱ),7,2′-二羟基-3′,4′-二甲氧基异黄烷-7-O-β-D-葡萄糖甙(Ⅲ),大豆皂甙Ⅰ,胡萝卜甙及β-谷甾醇。Ⅰ为新化合物,确定其结构为3-O-α-L-鼠李吡喃糖基(1→2)-D-木吡喃糖基-环黄芪醇。并应用二维核磁共振相关谱对Ⅱ和Ⅲ的¹H和¹³C化学位移信号进行了全面归属。

Abstract: Six compouns were isolated from the root of Astragalus chrysopterus Bunge. One of them was identified as a new triterpenoid glycoside, named astrachrysoside A. Its structure was elucidated as 3-O-α-L-rhamnopyranosyl (1→2) β-D-xylopyranosyl-cycloastragenol on the basis of physicochemical evidence and chemical reactions The others were shown to be known compounds, astrasieversianin ⅩⅤ (Ⅱ),7,2'-dihydroxy-3',4'-dimethoxy -isoflavane-7-O-β-D-glucoside (Ⅲ), soyasaponin Ⅰ, daucosterol and β-sitosterol. Full assignment of the chemical shift signals of Ⅱ and Ⅲ were estab-lished by various 2D-NMR techniques.