薯蓣皂素配基中加入6<i>α</i>-甲基

王资武, 黄鸣龙. 薯蓣皂素配基中加入6α-甲基J. 药学学报, 1962, 9(5): 265-270.

引用本文:

王资武, 黄鸣龙. 薯蓣皂素配基中加入6α-甲基J. 药学学报, 1962, 9(5): 265-270.

WONG TZU-WU HUANG MIN-LON, . THE INTRODUCTION OF C_6α-METHYL GROUP INTO DIOSGENINJ. Acta Pharmaceutica Sinica, 1962, 9(5): 265-270.

Citation:

WONG TZU-WU HUANG MIN-LON, . THE INTRODUCTION OF C_6α-METHYL GROUP INTO DIOSGENINJ. Acta Pharmaceutica Sinica, 1962, 9(5): 265-270.

薯蓣皂素配基中加入6α-甲基

摘要: 从薯蓣皂素配基出发,合成了C_6a-甲基化合物(Ⅷ).(Ⅷ)(R=Ac)用氯化亚硫酰或氧氯化磷处理,生成α-环氧化物(Ⅸ).

Abstract: From steroid sapogenin,diosgenin(Ⅰ),the C_6α-methyl compound(Ⅷ,R=H or Ac) has been prepared.It was converted into the α-oxide (Ⅸ) upon treatment with thionyl chloride or phosphorus oxychloride.

/