国产沉香化学成分的研究——Ⅴ.三个2-(2-苯乙基)色酮衍生物的分离和鉴定

STUDIES ON THE CHEMICAL CONSTITUENTS OF AQUILARIA SINENSIS (LOUR.) GILG. Ⅴ. ISOLATION AND CHARACTERIZATIOZ OF THREE 2-(2-PHENYLETHYL) CHROMONE DERIVATI VES

摘要: 自国产沉香(Lignum Aquiarilae sinensis)瑞香料(Thymeleaceae)植物乙醇提取物的醋酸乙酯溶解部分经硅胶层析,分寓得到三个2-(2-苯乙基)色酮衍生物。根据光谱(UV,IR,¹³C NMR,¹H NMR和MS)数据分析确定其中两个为新化合物;其结构分别为5,8-二羟基-2-(2-对甲氧基苯乙基)色酮(2)和6,7-二甲氧基-2-(2-对甲氧基苯乙基)色酮(3)。另外一个为已知化合物5,8-二羟基-2-(2-苯乙基)色酮,(1),是首次从该植物中得到。

Abstract: Three 2-(2-phenylethyl) chromone derivatives were isolated from the ethyl acetate soluble fraction of the alcoholic extract of Aquilaria sinensis (Lous.) Gilg. (Thymeleaceae) by silica gel chromatography. Based on spectral data (UV, IR, ¹HNMR, ¹³CNMR and MS) two of them are new compounds and their structures were identified as 5,8-dihydroxy-2-(2-p-methoxyphenylethyl) chromone (2) and 6,7-dimethoxy-2-(2-p-methoxyphenylethyl) chromone (3), The known compound siolated for the first time from this plant, was identified as 5,8-dihydroxy-2-(2-phenylethyl)-chromone (1).