覃兆海, 谢毓元. 铀促排药物研究VⅢ:邻苯二酚类鳌合剂的新法合成J. 药学学报, 1994, 29(12): 929-933.
引用本文: 覃兆海, 谢毓元. 铀促排药物研究VⅢ:邻苯二酚类鳌合剂的新法合成J. 药学学报, 1994, 29(12): 929-933.
shu
ZH Qin, YY Xie. STUDIES ON URANIUM MOBILIZATION AGENTS.VIII:NEW METHOD SYNTHSIS OF CHELATING AGENTS WITH CATECHOL RESIDUEJ. Acta Pharmaceutica Sinica, 1994, 29(12): 929-933.
Citation: ZH Qin, YY Xie. STUDIES ON URANIUM MOBILIZATION AGENTS.VIII:NEW METHOD SYNTHSIS OF CHELATING AGENTS WITH CATECHOL RESIDUEJ. Acta Pharmaceutica Sinica, 1994, 29(12): 929-933.
shu

铀促排药物研究VⅢ:邻苯二酚类鳌合剂的新法合成

STUDIES ON URANIUM MOBILIZATION AGENTS.VIII:NEW METHOD SYNTHSIS OF CHELATING AGENTS WITH CATECHOL RESIDUE

    摘要
  • Abstract: In further study on the synthesis of chelating agents with catechol residue,twoconvenient procedures-ethyl chloroformate method and dicyclohexylcarbodiimide(DCC)method-weredeveloped.The latter was used successfully to synthesize chelating agents with several catechol units.These compounds are more effective than compounds with only one catechol unit to detoxicate micewhich were under acute UO2(NO3)2 intoxication(LD95～100).

     

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