薯蓣属植物化学成分的研究——Ⅱ.叉蕊薯蓣中甾体皂甙的分离和鉴定

STUDIES ON THE CONSTITUENTS FROM DIOSCOREA PLANTS Ⅱ. ISOLATION AND IDENTIFICATION OF STEROIDAL SAPONINS FROM DIOSCOREA COLLETTII HOOK.F.

摘要: 从叉蕊薯蓣(D.collettii HooK.f.)根茎的乙醇提取物分离到四个甾体皂甙,根据理化性质、光谱数据,推定化学结构为3-O-(β-D-葡萄吡喃糖)-约莫皂甙元(3-O-(β-D-glucopyranosyl)-yamogenin)Ⅰ;3-O-α-L-鼠李吡喃糖(1→4)-β-D-葡萄吡喃糖-约莫皂甙元(3-O-α-L-rahmnopyranosyl(1→4)-β-D-glucopyranosyl-yamogenin)Ⅱ;3-O-α-L-鼠李吡喃糖(1→4)-α-L-鼠李吡喃糖(1→2)-β-D-葡萄吡喃糖-约莫皂甙元(3-O-α-L-rhamnopyranosyl(1→4)-α-L-rhamnopyranosyl(1→2)-β-D-glucopranosyl-yamogenin)Ⅲ;3-O-β-D-葡萄吡喃糖(1→3)-α-L-鼠李吡喃糖(1→2)3-β-D-葡萄吡喃糖-约莫皂甙元(3-O-β-D-glucopyranosyl(1→3)-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl-yamogenin)Ⅳ。其中Ⅰ为已知物,Ⅱ、Ⅲ、Ⅳ为首次从植物界得到的新甾体皂甙。

Abstract: Four steroidal saponins, collettinside Ⅰ, Ⅱ, Ⅲ and Ⅳ, were isolated from the rhizomes of Dioscorea collettii Hook. f. collected from Si Chuan Province. Their chemical structures have been elucidated by means of chemical and spectrometric analyses as 3-O-(β-D-glucopyranosyl)-yamogenin Ⅰ; 3-O-α-L-rhamno pyranosyl (1→4)-β-D-glucopyranosyl-yamogenin Ⅱ; 3-O-α-L-rhamnopyranosyl (1→4)-α-L-rhamnopyranosyl (1→2)-β-D-glucopranosyl-yamogenin Ⅲ; 3-O-(β-D-glucopyranosyl (1→3)-α-L-rhamnopyranosyl (1→2)-β-D-glucopyranosyl)-yamogenin Ⅳ. Colllettinside Ⅱ, Ⅲ and Ⅳ are new steroidal saponins.