可逆性胆碱酯酶抑制剂:二甲氨基甲酸-5-(1,3,3-三甲基-6-取代基)吲哚满酯的合成
SYNTHESIS OF 5-(1, 3, 3-TRIMETHYL-6-SUBSTITUTED) INDOLINYL N, N-DIMETHYLCARBAMATES AS REVERSIBLE CHOLINESTERASE INHIBITORS
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Abstract: A series of 5-(1,3,3-trimethyl-6-substituted) indolinyl N, N-dimethylcarbamates, aromatic ring substituted derivatives of CUI XING NING, was prepared for evaluation of their pharmacological activity. Compounds I8 and I11~I14 were found to have the same order of anticholinesterase activity as CUI XING NING.
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