茜草中蒽醌类成分的研究

STUDIES ON ANTHRAQUINONES FROM THE ROOTS OF RUBIA CORDIFOLIA L.

摘要: 从茜草Rubia cordifolia L.根的乙醇提取物中分得七个蒽醌类化合物,经理化性质及光谱分析,分别鉴定为1,3,6-三羟基-2-甲基蒽醌(Ⅰ),1-羟基蒽醌(Ⅱ),1,2,4-三羟基蒽醌(Ⅲ),1,3,6-三羟基-2-甲基蒽醌-3-O-β-D-吡喃葡萄糖甙(Ⅳ),1,2-二羟基蒽醌-2-O-β-D-吡喃木糖(1→6)-β-D-吡喃葡萄糖甙(Ⅴ),1,3-二羟基-2-羟甲基蒽醌-3-O-β-D-吡喃木糖(1→6)-β-D-吡喃葡萄糖甙(Ⅵ)及1,3,6-三羟基-2-甲基蒽醌-3-O-β-D-吡喃木糖(1→2)-β-D-(6'-O-乙酰基)吡喃葡萄糖甙(Ⅶ).其中Ⅶ为一新化合物。

Abstract: Seven anthraquinones were isolated from the ethyl alcohol extracts of the roots ofRubia Cordifolia L.. By means of spectrometric data combined with physico-chemical properties, six ofthem wewre identified as 2-methyl-1, 3, 6-trihydroxy-9,10-anthraquinone (Ⅰ), 1-hydroxy-9, 10-anthraquinone (Ⅱ), 1, 2,4-trihydroxy-9, 1 0-anthrequinone (Ⅲ), 2-methyl-1, 3, 6-trihydroxy-9, 10-anthraquinone-3-O-β-D-glucoside(Ⅳ), 1, 2-dijhydroxy-9, 10-anthraquinone-2-O-β-D-xylosyl (1→6)-β-D-glucoside (Ⅴ) and 1,3-dihydroxy-2-hydroxymethy 1-9, 10-anthraquinone-3-O-β-D-xylosyl(1→6)-β-D-glucoside(Ⅵ). Ⅶ is a new compound. Its structure was elucidated to be 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-β-D-xylosyl (1→2)-β-D-(6'-O-acetyl)glucoside.