Abstract:
Fourteen constituents(V
1~V
14) were isolated from
Veratrum stenophyllum Diels. Eight of them were identified as known compounds. Among the remaining constituents the structure of stenophylline A (V
3), B (V
6) and B
1-Chaconine (V
12) as well as partial structure of stenophylline C (V
10) and D (V
14) have been elucidated. Another one has not been identified. V
3,V
6,V
10 and V
14 are new compounds, V
12 has not been found previously in Veratrum plants. The weak alkaloid fraction of the plant and V
3 were shown to have significant activity in lowering blood pressure and heart rate on anesthetic cat.