血吸虫病化学治疗的研究——ⅩⅣ.香豆满(Coumaran)衍生物及其类似物的合成
CHEMOTHERAPEUTIC STUDIES ON SCHISTOSOMIASIS ⅩⅣ. SYNTHESIS OF COUMARAN DERIVATIVES AND ITS ANALOGS
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Abstract: Ten coumaran derivatives were synthesized from the corresponding 2,2'-diphenoI methane or 2,2'-diphenol sulfide derivatives by oxidation. In preliminary screening for prophylactic and curative activities against experimental infection of Schistosomiasis japonica in mice, compound Ⅱ2 was found to be the most active.
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