陈若芸, 于德泉. 新疆藁本有效成分研究J. 药学学报, 1995, 30(7): 526-530.
引用本文: 陈若芸, 于德泉. 新疆藁本有效成分研究J. 药学学报, 1995, 30(7): 526-530.
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RY Chen, DQ Yu. STUDIES ON THE CHEMICAL CONSTITUENTS OF CONISELINUM V AGINATUM THELLJ. Acta Pharmaceutica Sinica, 1995, 30(7): 526-530.
Citation: RY Chen, DQ Yu. STUDIES ON THE CHEMICAL CONSTITUENTS OF CONISELINUM V AGINATUM THELLJ. Acta Pharmaceutica Sinica, 1995, 30(7): 526-530.
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新疆藁本有效成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF CONISELINUM V AGINATUM THELL

    摘要
  • 摘要: 从新疆藁本(ConiselinumvaginatumThell)的根茎中分到七个化合物,根据理化常数和光谱解析,分别鉴定为coniselin(Ⅰ),(E)-3-methoxy-4,5-methyenedioxycinnamicaldehyde(Ⅱ),(E)-3-methoxy-4,5-methylenedioxycinnamicalcohol(Ⅲ),(E)-3-methoxy-4,5-methylenedoxycinnamicacid(Ⅳ),肉豆劳动蔻酸(myristicicacid,V),阿魏酸(ferulicacid,Ⅵ)和香草醛(vanilin,Ⅶ)。其中Ⅰ为新化合物,其余均为首次从该植物中分到。经药理实验表明化合物Ⅱ～Ⅴ对四氯化碳引起的小鼠转氨酶升高有降低作用,对丙酸杆菌引起的小鼠免疫性肝损伤有保护作用。

     

    Abstract: Seven compounds were isolated from the alcoholic extract of Comiselinum vaginatum Thell.On the basis of their chemical properties and spectral data (MS. UV.IR. 1H AND 13CNMR)they were identified as conioselin,)-3-methoxy-4,5-methylenedioxycinnamic aldehyde(Ⅱ),(E)-3-methoxy -4,5-methylejnedioxycinnamic alcohol(Ⅲ),(E)-3- methoxy- 4 ,5-methylenedioxy-cinnamic acid (Ⅳ),myristicic acid (Ⅴ),ferulic acid (Ⅵ) and vanilin).Compound Ⅰ is a new compound,compounds Ⅱ,Ⅲ,Ⅳ,Ⅴ,Ⅵ and Ⅶ were obtained fOr the first time from the titleplant.

     

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