胡润生, 李宝珍, 陈玫. 滨蒿 利胆有效成分的研究——Ⅰ.提取物的水溶部分J. 药学学报, 1965, 12(5): 289-294.
引用本文: 胡润生, 李宝珍, 陈玫. 滨蒿 利胆有效成分的研究——Ⅰ.提取物的水溶部分J. 药学学报, 1965, 12(5): 289-294.
HU RUN-SHENG AND LI BAO-ZHEN CHEN MEI, . CHOLERETIC PRINCIPLES OF ARTEMISIA SCOPARIA Ⅰ. WATER SOLUBLE FRACTION OF ITS EXTRACTJ. Acta Pharmaceutica Sinica, 1965, 12(5): 289-294.
Citation: HU RUN-SHENG AND LI BAO-ZHEN CHEN MEI, . CHOLERETIC PRINCIPLES OF ARTEMISIA SCOPARIA Ⅰ. WATER SOLUBLE FRACTION OF ITS EXTRACTJ. Acta Pharmaceutica Sinica, 1965, 12(5): 289-294.

滨蒿 利胆有效成分的研究——Ⅰ.提取物的水溶部分

CHOLERETIC PRINCIPLES OF ARTEMISIA SCOPARIA Ⅰ. WATER SOLUBLE FRACTION OF ITS EXTRACT

  • 摘要: 滨蒿(Artemisia scoparia Waldst et Kit.)为四种商品茵陈蒿中之一种,从其提取物的水溶部分分离得到具有利胆作用的成分绿原酸.它的加碱水解产物咖啡酸也具有利胆作用,含量约占生药的0.4%.此外,并分离确证有胆碱存在.从其他几种商品茵陈蒿(包括A.capillaris Thunb.在内)也能得到咖啡酸,但得量高低悬殊,从微量到0.85%.虽然滨蒿花蕾中也含6,7-二甲氧基香豆素0.5%,但从其幼苗中却未检出此成分.

     

    Abstract: Dried young herbs of Artemisia scoparia Waldst et Kit. is one of the four commer- cial varieties of Ing-chen-hao, a drug used in Chinese Medicine for the treatment of jaundice. Chlorogenic acid, a choleretic principle, has been isolated from the water soluble fraction of its extract, which upon alkaline hydrolysis produced caffeic acid in yields around 0.4% of the crude drug. Besides, choline was identified and isolated from this fraction. Caffeic acid also possesses choleretic activity. It has also been obtained from other varieties of the drug including A. capillaris Thunb. However, yields varied widely from a bare trace to 0.85%. Although 6,7-dimethoxycoumarin occurred in flower buds in 0.5%, yet it was absent from the young herbs of Artemisia scoparia.

     

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