槲寄生化学成分的研究——Ⅲ.槲寄生新甙Ⅲ,Ⅴ,Ⅵ的结构

STUDIES ON THE CHEMICAL COMPONENTS OF VISCUM COLORATUM——Ⅲ. STRUCTURE OF VISCUMNEOSIDE Ⅲ, Ⅴ AND Ⅵ

摘要: 自槲寄生(Viscum coloratum(Kom.) Nakai)中分离得到五个黄酮甙。经光谱和化学分析确定Ⅰ为异鼠李素-3-O-β-D-葡萄糖甙,Ⅱ为异鼠李素-7-O-β-D-葡萄糖甙,Ⅲ为高圣草素-7-O-β-D-芹菜糖基(1→2)-β-D-葡萄糖甙;Ⅴ为高圣草素-7-O-β-D-芹菜糖(1→5)-β-D-芹菜糖(1→2)-β-D-葡萄糖甙;Ⅵ为高圣草素-7-O-β-D-(6″-乙酰)-葡萄糖甙。化合物Ⅲ,Ⅴ,Ⅵ为三个新的双氢黄酮甙,分别命名为槲寄生新甙Ⅲ(viscumneoside Ⅲ),槲寄生新甙Ⅴ(viscumneoside Ⅴ)和槲寄生新甙Ⅵ(viscumneoside Ⅵ)。Ⅰ和Ⅱ亦系首次从该植物中发现。

Abstract: Viscum coloratum (Kom.) Nakai is a well-known traditional Chinese medicine. For the exploration of the active principles, the chemical components of this drug were studied. Five compounds were isolated. Based on chemical and spectroscopic analysis, the structure of Ⅰ, Ⅱ, Ⅲ, Ⅴ, Ⅵ have been elucidated as isorhamnetin-3-O-β-D-glucoside, isorhamnetin-7-O-β-D-glucoside, homoeriodictyol-7-O-β-D-apiosyl-(1→2)-β-D-glucopyranoside, homoeriodictyol-7-O-β-D-apiosyl(1→5)-β-D-apiosyl(1→2)-β-D-glucopyranoside and homoeriodictyol-7-O-β-D-(6″O-acetyl)-glucopyranoside, respectively. Ⅲ, Ⅴ and Ⅵ are three new flavanone glycosides and named viscumneoside Ⅲ, viscumneoside Ⅴ and viscumne oside Ⅵ, respectively. Two other compounds (Ⅰ, Ⅱ) were found in this genus for the first time.