Abstract: The anion of potassium antimony tartrate was found to be capable of combining with a weakly basic anion exchange resin and a resin antimony tartrate was thus prepared. When the resin antimony tartrate was eluted with artificial gastric juice or with arti- ficial intestinal juice, the effluates were found to contain 4.7% and 29.1% of the total antimony respectively, indicating that resin antimony tartrate may be used as an enteric preparation. In the absorption experiments resin antimony tartrate appeared to cause a steady re- lease of antimony over a relatively long period, as the peak of blood Sb level was reached during 9 to 24 hours after a single dose. When a course of treatment with resin antimony tartrate was given, blood antimony levels, determined before giving the next dose, were found to vary between 1 and 3.5μg Sb/10 ml. Therapeutic test with this preparation was conducted on 9 dogs. The average number of worms in the treated animals was reduced to 14% of that of the controls. During the experiments of absorption and experimental therapy emesis was observed 29 times, diarrhoea 21 times, and anorexia 154 times for a total of 224 doses of the preparation in 10 dogs. Thus with this new oral preparation the gastro-intestinal reac- tions were considerably reduced, but not completely abolished. From these results it is considered that resin antimony tartrate may serve as a new possibility for researches on the oral preparation of tartar emetic.