刘发, 魏苑, 杨新中, 李芳桂, 胡坚, 程瑞芬. 红花黄素对高血压大鼠的降压作用及对肾素-血管紧张素的影响J. 药学学报, 1992, 27(10): 785-787.
引用本文: 刘发, 魏苑, 杨新中, 李芳桂, 胡坚, 程瑞芬. 红花黄素对高血压大鼠的降压作用及对肾素-血管紧张素的影响J. 药学学报, 1992, 27(10): 785-787.
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F Liu, Y Wei, XZ Yang, FG Li, J Hu, RF Cheng. HYPOTENSIVE EFFECTS OF SAFFLOWER YELLOW IN SPONTANEOUSLY HYPERTENSIVE RATS AND INFLUENCE ON PLASMA RENIN ACTIVITY AND ANGIOTENSIN II LEVELJ. Acta Pharmaceutica Sinica, 1992, 27(10): 785-787.
Citation: F Liu, Y Wei, XZ Yang, FG Li, J Hu, RF Cheng. HYPOTENSIVE EFFECTS OF SAFFLOWER YELLOW IN SPONTANEOUSLY HYPERTENSIVE RATS AND INFLUENCE ON PLASMA RENIN ACTIVITY AND ANGIOTENSIN II LEVELJ. Acta Pharmaceutica Sinica, 1992, 27(10): 785-787.
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红花黄素对高血压大鼠的降压作用及对肾素-血管紧张素的影响

HYPOTENSIVE EFFECTS OF SAFFLOWER YELLOW IN SPONTANEOUSLY HYPERTENSIVE RATS AND INFLUENCE ON PLASMA RENIN ACTIVITY AND ANGIOTENSIN II LEVEL

    摘要
  • Abstract: Safflower yellow (SY) is a mixture of chalconoid compounds extracted from Carthamus tinctorius L. Ig SY 1～2 g·kg-1·d-1lowered the blood pressure of spontaneously hypertensiverats (SHR), for about 1.86～3.86 kPa. Five weeks after administration of SY, the plasma renin ac-tivity and angiotensin Ⅱ level diminished in the SHR experimental groups. These suggest that the de-crease of blood pressure is mediated by the renin-angiotensin system.

     

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