桉叶苷的分离和结构

ISOLATION AND STRUCTURE OF CAMALDULENSIDE FROM EUCALYPTUS CAMALDULENSIS VAR. PENDULA BLAK. ET JACOBS

摘要: 目的　研究垂枝赤桉Eucalyptus camaldulensis var. pendula Blak. et Jacobs叶的化学成分。方法　采用各种色谱技术进行分离纯化，用IR, MS, ¹HNMR, ¹³CNMR(DEPT), ¹H-¹H COSY, ¹³C-¹H COSY, COLOC和X-射线单晶衍射鉴定化合物。结果　分离得到了5个化合物：三十烷醇(I)，β-谷甾醇(II),对羟基苯甲酸(III), 胡萝卜苷(IV), 5,7-二羟基-2-甲基-苯骈吡喃酮-7-O-β-D-6-O-［4R-(1-甲基-1-羟基)-乙基环己-1-烯］-甲酰基-吡喃葡糖(V)。结论　所有化合物均为首次从该植物中分得，V为一个新化合物，命名为桉叶苷(camaldulenside)。

Abstract: AIM　To study the chemical composition of the leaves of Eucalyptus camaldulensis var. pendula Blak. et Jacobs. METHODS　Column chromatography was used to separate the chemical constituents. IR, MS, ¹HNMR, ¹³CNMR, ¹H-¹H　COSY, ¹³C-¹H　COSY and X-ray diffraction were used to determine the structures of the isolated constituents. RESULTS　Five compounds were identified by spectral analyses as 1-triacotanol(I),　β-sitosterol(II), 4-hydroxybenzoic acid(III), β-sitosterol-3-O-β-D-glucopyranoside(IV) and camaldulenside(V). CONCLUSION　All compounds were obtained from Eucalyptus camaldulensis var. pendula Blak. et Jacobs for the first time. Among them, compound V is a new one.