Abstract: Apiopaeonoside, a new compound, was isolated from the root of Paeonia suffruticosa Andr. Its structure was elucidated as paeonol-D-apio-β-D-furanosyl (1→6)-β-D-glucopyranoside on the basis of spectral data, hydrolytic reaction and preparation of derivatives.The other 5 compounds isolated were paeoniflorin, benzoylpaeoniflorin, paeonol, paeonoside and paeonolide. The physical constants and spectral data of paeonoside and paeonolide were also reported.