To explore the influence of matrix materials in complicate ingredients on traditional Chinese medicine and investigate the excipients selection model based on balanced release characteristics of multi-  components, the influence of HPMC (K4M, K15M, K100M) and Carbomer (934P, 971P, 974P) was illustrated  by testing in vitro release of ginsenoside-Rg₁, ginsenoside-Rb₁ and notoginsenoside-R₁ in Panax notoginseng saponins (model drug, PNS).  According to in vitro release results of PNS matrix tablets in water and artificial intestinal juice, the release curves were analyzed with Peppas equation and simulating factor (f₂).  Significant differences in k value and n value among ginsenoside-Rg₁, ginsenoside-Rb₁ and notoginsenoside-R₁ existed in various formulations.  The release behaviors from various excipients could be described with Non-Fickian transport or super Case Ⅱtransport pattern.  The f₂ values for ginsenoside-Rg₁, ginsenoside-Rb₁ and notoginsenoside-R₁ in 971P matrix tablet containing 30% Carbomer 971P were 74.91, 53.45, 57.89 in water and 79.35, 55.51, 51.89 in artificial intestinal juice, respectively.  The release profiles fit for the regulation of FDA.  The result revealed that the balanced release rates of Rg₁, Rb₁ and R₁ in 971P matrix tablet were obtained.