海南粗榧内酯(Hainanolide)的抗病毒作用
THE ANTIVIRAL EFFECT OF HAINANOLIDE, A COMPOUND ISOLATED FROM CEPHALOTAXUS HAINANENSIS
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Abstract: Hainanolide in tissue culture was noticed to have a plaque formation inhibiting activity against influenza virus type A (WS), Newcastle disease virus, Japanese B encephalitis virus (A 2) and vaccina virus. The maximal tolerated dose of the drug was 0.5 μg/disc. The minimal antiviral doses of the drug were 0.05~0.5μg/disc. The zone of inhibition against viruses extended about 15~50 mm wide.
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