海南萝芙木季胺碱——大斯配加春的结构

THE QUATERNARY ALKLOID OF RAUWOLFIA VERTICILLATA (LOUR.) BAILL VAR. HAINANENSIS TSIANG.——STUDIES ON THE STRUCTURE OF MACROSPEGATRINE

摘要: 从海南萝芙木生产“降压灵”的母液中,分得一新的二聚体生物碱,命名为大斯配加春(macrospegatrine)。根据红外、紫外、质谱、氢谱及单晶X—射线衍射确定结构为Ⅰ式(图1)。

Abstract: A new bis-indolo alkaloid, macrospegatrine isolated from the water soluble fraction of the roots of the title species of Rauwolfia was shown to have the molecular formula C₄₀H₄₆N₄O₃Cl₂. On the basis of UV, IR, MS and NMR spectroscopic data evidence, particularly X-ray crystallographic analysis, structure 1 has been assigned to this alkaloid.