亚麻子油饼的化学成分研究
Chemical constituents from the linseed meal
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摘要:
本文对亚麻子油饼中的非木脂素类化学成分进行了研究。通过大孔树脂、硅胶、葡聚糖凝胶Sephadex LH-20柱色谱和HPLC等多种色谱分离方法, 从亚麻 (Linum usitatissimum L) 子榨油后油饼的70% 乙醇提取物中分离得到10个化合物。利用红外光谱、核磁共振等现代波谱学技术, 结合化合物理化性质和质谱数据, 鉴定其结构分别为: 1-甲基乙基-2-O-β-D-吡喃葡萄糖基-(1''→6')-β-D-吡喃葡萄糖苷 (1)、亚麻苷 (2)、亚麻新苷 (3)、百脉根苷 (4)、亚麻苦苷 (5)、脱氧鸟苷 (6)、腺苷 (7)、(+)-松脂酚-4'-O-β-D-吡喃葡萄糖苷 (8)、4-O-β-D-吡喃葡糖基香草醇 (9) 和2-甲氧基对苯二酚-1-O-β-D-吡喃葡萄糖苷 (10)。其中, 化合物1为新双糖苷类化合物, 化合物6~10为首次从亚麻子中分离得到。
Abstract:Ten compounds were isolated from the 70% ethanol extract of linseed meal (Linum usitatissimum L) through a combination of various chromatographic techniques, including silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC. On the basis of spectroscopic data analysis, they were elucidated as 1-methylethyl-2-O-β-D-glucopyranosyl-(1''→6')-β-D-glucopyanoside (1), linustatin (2), neolinustatin (3), lotaustralin (4), linamarin (5), deoxyguanosine (6), deoxyadenosine (7), (+)-pinoresinol-4'-O-β-D-glucopyranoside (8), 4-O-β-D-glucopyranosylvanillyl alcohol (9) and tachioside (10), separately. Among them, compound 1 is a new compound, and compounds 6, 8 and 10 were isolated from the linseed meal for the first time.
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