Abstract: A gas chromatographic method of quantitative determination and identification for compound tablets of theophylline was studied. Six components in compound tablets of theophyline were successfully separated and simultaneously quantitatively determined and identified without any pretreatment. The glass column (1.6m×3mm ID) was packed with Chromosorb W (AW-DMCS, 60～80 mesh) coated with 2% OV-17 and operated at 225℃. The mean recoveries with coefficient of variation (CV%) are 99.47% (0.86%) for ephedrine hydrochloride, 100.3%(0.3%), for phenacetin, 100.4% (1.1%) for caffeine, 100.8% (0.64%) for aminopyrine, 102.4% (1.4%) for phenobarbital, 100.0% (1.4%) for theophylline, respectively. The results obtained are satisfactory both in recovery and in precision. It is a simple, rapid and specific method.