可变误差多面体法用于多种维生素的同时测定

SPECTROPHOTOMETRIC DETERMINATION OF MULTICOMPONENT VITAMINS BY FLEXIBLE TOLERANCE SIMPLEX METHOD

摘要: 本文基于对多元校正分析模型的简要讨论,探索了应用可变误差多面体法同时测定维生索B₁,B₂,B₆和烟酰胺的可行性。其结果准确度和精密度均较满意。维生素B₁,B₂,B₆及烟酰胺的回收率分别是99.8±0.9%(CV),100.1±0.8%(CV),100.2±2.1%,100.1±0.7%(CV)。结果表明,通过公式K_S=A_SC_S^T(C_SC_S^T)^-1计算校正系数矩阵K_S,并结合可变误差多面体法这一直接求解方法,能有效地提高分析结果的准确度,克服组分间的交互作用及病态,是多元校正分析的较佳策略之一。

Abstract: Based on the brief discussion of error propagation in multivariate calibration and analysis, the flexible tolerance simplex method (FTSM) was applied to analyze vitamin B₁, B₂, B₆ and niacinamide simultaneously. The results obtained were comparatively satisfactory both in precision and in accuracy. The average recoveries of vitamin B₁, B₂, B₆ and niacinamide were 99.8±0.9%(CV), 100.1±0.8%(CV), 100.2±2.1% (CV) and 100.1±0.7% (CV)respectively. All these show that FTSM, with calibration matrix K calculated from K= A_SC_S^T (C_SC_S^T)^-1; is one of the most efficient procedures for improving accuracy, especially when there are interactions between variables and the problem is ill-conditioned.