仙鹤草根芽中新异香豆精甙的结构研究

STUDIES ON THE STRUCTURE OF A NEW ISOCOUMARIN GLUCOSIDE OF THE ROOTSPROUTS OF AGRIMONIA PILOSA LEDEB

摘要: 从仙鹤草根芽的苯提取物和丙酮提取物中分得反式对羟基肉桂酸酯的同系物混合物(Ⅵ)和一个新的异香豆精甙(Ⅶ)。通过理化性质,波谱分析(UV,IR,¹HNMR,MS,CI-MS-MS)及化学降解,Ⅵ被确定为反式对羟基肉桂酸C₂₂,C_24～32,C₃₄直链一元饱和醇的酯,Ⅶ被确定为仙鹤草内酯-6-O-β-D-葡萄吡喃糖甙。其中Ⅶ和反式对羟基肉桂酸C_20～32,C₃₄直链一元饱和醇酯为新化合物。

Abstract: Trans-p-hydroxycinnamic esters Ⅵ and an isocoumarin glucoside Ⅶ were isolated from the benzene and acetone extracts of the rootsprouts of Agrimonia pilosa Ledeb. On the basis of physicochemical properties, spectral data(UV,IR,NMR,MS,CI-MS-MS), GC and chemical degradation, Ⅵ was elucidated as trans-p-hybroxycinnamic esters of n-C₂₂,n-C_24～32,n-C₃₄,alcohols, Ⅶ was elucidated as agrimonolide-6-O-β-D-glucopyranoside. Ⅶ and trans-p-hydroxycinnamic esters of n-C_29～32 and n-C₃₄ alcohols are new compounds.