王本祥, 崔景朝, 刘爱晶. 人参茎叶皂甙促进动物生长的作用J. 药学学报, 1982, 17(12): 899-904.
引用本文: 王本祥, 崔景朝, 刘爱晶. 人参茎叶皂甙促进动物生长的作用J. 药学学报, 1982, 17(12): 899-904.
WANG Ben-xiang, CUI Jing-chao , LIU Ai-jing, . THE ACTION OF GINSENOSIDES EXTRACTED FROM THE STEMS AND LEAVES OF PANAX GINSENG IN PROMOTING ANIMAL GROWTHJ. Acta Pharmaceutica Sinica, 1982, 17(12): 899-904.
Citation: WANG Ben-xiang, CUI Jing-chao , LIU Ai-jing, . THE ACTION OF GINSENOSIDES EXTRACTED FROM THE STEMS AND LEAVES OF PANAX GINSENG IN PROMOTING ANIMAL GROWTHJ. Acta Pharmaceutica Sinica, 1982, 17(12): 899-904.

人参茎叶皂甙促进动物生长的作用

THE ACTION OF GINSENOSIDES EXTRACTED FROM THE STEMS AND LEAVES OF PANAX GINSENG IN PROMOTING ANIMAL GROWTH

  • 摘要: 人参茎叶皂甙可促进未成年小鼠、大鼠及猪体重的增长,其同化作用与雄性同化类固醇不同,因其在增加大鼠体重时,并未增加提肛肌—海绵球肌及前列腺—贮精囊重量。人参茎叶皂甙的同化作用可能与其促进RNA和蛋白质合成作用有关系。本文还报告了人参茎叶皂甙的急性毒性和亚急性毒性实验结果。

     

    Abstract: In this paper, the action of ginsenosides extracted from stems and leaves of ginseng (GSL) in promoting animal growth was investigated. When GSL was given ip or po to young mice or fats, a marked increase of body weight of the animals was, noted. Oral administration of GSL (40 or 80 mg/kg) was also effecive. In addition, GSL speeded up the growth of young pigs. It was found that the protein and RNA contents of muscles and liver in GSL-treated rats increased markedly, but no increase. of the weight of the prostate-seminal vesicle and levator ani-bulbocavernosus muscles was observed. It appears that the anabolic action of GSL is different from that the androgenic steroids. The promotion of animal growth of GSL is due to its direct influence on syntheses of RNA and protein. The acute and subacute toxicities of GSL were also reported.

     

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