陈葆仁, 杨义芳, 田如美, 张长盘, 萧幼静, 刘铭勋. 赣皖乌头生物碱的研究——Ⅰ.赣皖乌头中生物碱的分离与鉴定J. 药学学报, 1981, 16(1): 70-72.
引用本文: 陈葆仁, 杨义芳, 田如美, 张长盘, 萧幼静, 刘铭勋. 赣皖乌头生物碱的研究——Ⅰ.赣皖乌头中生物碱的分离与鉴定J. 药学学报, 1981, 16(1): 70-72.
Chen Baoren, Yang Yifang, Tian Rumei, Zhang Ghangpan, Xiao Youzing , Liu Mingxun, . ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZJ. Acta Pharmaceutica Sinica, 1981, 16(1): 70-72.
Citation: Chen Baoren, Yang Yifang, Tian Rumei, Zhang Ghangpan, Xiao Youzing , Liu Mingxun, . ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZJ. Acta Pharmaceutica Sinica, 1981, 16(1): 70-72.

赣皖乌头生物碱的研究——Ⅰ.赣皖乌头中生物碱的分离与鉴定

ALKALOIDS OF ACONITUM FINETIANUM HAND-MAZZⅠ. ISOLATION AND IDENTICATION OF ALKALOIDS FROM ACONITUM FINETIANUM HAND-MAZZ

  • Abstract: Five alkaloids were isolated from the roots of Aconitum finetianum (Hand-Mazz.) by a combination of pH extraction and chromatographic techniques. Chemical and spectral studies suggested that they are a series of the lycoctonine-type alkaloid. Three of them were identified as delsoline, avadharidine and lycoctonine, by comparing their physical properties with known compounds. The formulas of two others alkaloids are designated as C27H21N3O5(141~142℃) and C22H31NO3 (221~226℃). Their structures are under investigation. Delsoline is useful for acute dysentery, acute enteritis and a relaxant of the smooth muscle of intestines.

     

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