6α-甲基强的松龙乙酸酯的合成

蔡祖恽, 程起陆, 余新娣, 倪元. 6α-甲基强的松龙乙酸酯的合成J. 药学学报, 1982, 17(3): 233-235.

引用本文:

蔡祖恽, 程起陆, 余新娣, 倪元. 6α-甲基强的松龙乙酸酯的合成J. 药学学报, 1982, 17(3): 233-235.

CAI Zu-yun, CHENG Oi-lu, YU Xin-di , NI Yuan, . SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATEJ. Acta Pharmaceutica Sinica, 1982, 17(3): 233-235.

Citation:

CAI Zu-yun, CHENG Oi-lu, YU Xin-di , NI Yuan, . SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATEJ. Acta Pharmaceutica Sinica, 1982, 17(3): 233-235.

SYNTHESIS OF 6α-METHYL PREDNISOLONE ACETATE

Abstract: 6α-Methyl prednisolone acetate (Ⅸ) was synthesized from 6α-methyl-11β, 17α-dihydroxy progesterone (Ⅶ), which had been obtained through six steps (Ⅰ→Ⅱ→Ⅲ→Ⅳ→Ⅴ→Ⅵ→Ⅶ). The overall yield from Ⅰ to Ⅶ was 17.3%.

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