忻涛, 丁健, 张秀平. 1-氨基-6-氟-1,4-二氢-4-氧代-7-(取代)哌嗪基-3-喹啉羧酸及其衍生物的合成与抗菌活性J. 药学学报, 1993, 28(11): 865-869.
引用本文: 忻涛, 丁健, 张秀平. 1-氨基-6-氟-1,4-二氢-4-氧代-7-(取代)哌嗪基-3-喹啉羧酸及其衍生物的合成与抗菌活性J. 药学学报, 1993, 28(11): 865-869.
shu
T Xin, J Ding , XP Zhang, . SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF 1-AMINO-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(SUBSTITUTED) PIPERAZINYL-3-QUINOLINECARBOXYLIC ACIDS AND THEIR DERIVATIVESJ. Acta Pharmaceutica Sinica, 1993, 28(11): 865-869.
Citation: T Xin, J Ding , XP Zhang, . SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF 1-AMINO-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(SUBSTITUTED) PIPERAZINYL-3-QUINOLINECARBOXYLIC ACIDS AND THEIR DERIVATIVESJ. Acta Pharmaceutica Sinica, 1993, 28(11): 865-869.
shu

1-氨基-6-氟-1,4-二氢-4-氧代-7-(取代)哌嗪基-3-喹啉羧酸及其衍生物的合成与抗菌活性

SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF 1-AMINO-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(SUBSTITUTED) PIPERAZINYL-3-QUINOLINECARBOXYLIC ACIDS AND THEIR DERIVATIVES

    摘要
  • Abstract: The title compounds 6～24 were obtained by the reaction of 5 with corresponding benzaldehydes. 5 wes prepared with ethyl 7-chloro-6-fluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylate by hydrolysis, amination and condensation with piperazine. Anti—bacterical activities of 5～24 were tested in vitro.

     

    • HTML全文
    • 参考文献(0)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回