榼藤子含硫酰胺类化学成分的研究(英文)
Sulfur-containing amides from Entada phaseoloides
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摘要:
为研究榼藤子 Entada phaseoloides (L.) Merr. 种仁的化学成分, 利用正反相硅胶柱色谱、制备HPLC分离纯化, 通过现代波谱学技术鉴定结构。从70% 乙醇提取物的正丁醇萃取部位分离得到4个含硫酰胺类化合物, 分别为entadamide A-β-D-glucopyranosyl-(1→3)-β-D-glucopyranoside (1)、entadamide A (2)、entadamide A-β-D- glucopyranoside (3) 和clinacoside C (4)。化合物1为新化合物, 化合物4为首次从该属中分离得到。
Abstract:To study the chemical constituents of the Entada phaseoloides (L.) Merr., seeds of Entada phaseoloides were extracted with 70% ethanol at room temperature. Isolation and purification were performed by silica gel, reversed-phase silica gel column chromatography and semi-preparative HPLC. Structures of the pure compounds were established on the basis of spectral analysis. Four sulfur-containing amide compounds were isolated from the n-BuOH-soluble fraction and identified as entadamide A-β-D-glucopyranosyl-(1→3)-β-D- glucopyranoside (1), entadamide A (2), entadamide A-β-D-glucopyranoside (3) and clinacoside C (4). Compound 1 is a new compound. Compound 4 is isolated from the genus Entada for the first time.
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