中国乌头对血管的作用
The Effect of Fu-Tze (Aconitum Carmichaeli Debx.) on Blood Vessel of Animals
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摘要: 南京地区所产的乌头及四川所产的熟附片所作成的煎剂对麻醉动物可引起迅速而暂短的降压,此时心脏功能尚无显著变化,故降压与血管有密切关系。用本实验室自制的末梢阻力测定装置测得,熟附片煎剂能引起下肢血管的显著扩张,而乌头煎剂作用较小,降压可被大量阿托品或苯海拉明所消除,此外它尚能扩张冠状血管,而此与血压或心率无关。Abstract: The effect of decoctum of Fu-Tze on the blood vessels had been studied. Blood pressure of anaesthetized animal had a rapid,short-durationed drop without significant change of heart function.This depression could be eliminated or blocked by atropine and benadryl.With modified Khayutin's apparatus it has been shown that decoctum has a significant, direct vasodilatation on the blood vessel of muscle of hind limb, probably owing to the muscaline-like or histamine-like substences it contains. With the Caverina's method a coronal vasodilatation, indenpedent of blood pressure and heart rate, has also been observed.
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