Abstract: Lamiophlomis rotata (Labiatae) is a Chinese folk medicinal plant in Xi-zang(Tibet), which has effects of promoting blood circulation to remove blood stasis, subduing swelling and alleviating pain. Four iridoid glucosides were isolated from the root of the species. On the basis of IR, UV, NMR, MS spectral data and chemical methods, their structures were identified as: 8-O-acetylshanzhiside methyl ester(I), 6-O-acetylshanzhiside methyl ester(II), penstemoside(III) and 7,8-dehydropenstemoside(IV). The last one is a new compound.