抗沙眼新药肽丁安类似物的合成
SYNTHESIS OF ANALOGS OF TAI-DING-AN, A NEW DRUG FOR TREATMENT OF CHLAMYDOZOA TRACHOMATIS
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Abstract: Tai-Ding-An, an effective agent against chlamydozoa-trachomatis and herpes virus, has been used in clinical trial. Because of its poor water solubility, eight new analogs were syhthesized by direct condensation of the appropriate aldehydes and 3-amino substituted ketones with thiosemicarbazide.
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