赤芝子实体中三萜化学成分的研究

STUDIES ON THE TRITERPENOID CONSTITUENTS FROM THE FRUITING BODY OF GANODERMA LUCIDUM (FR.)KARST.

摘要: 自赤芝Ganoderma lucidum (Fr.)Karst的二氯甲烷溶解部分分离得到一个新的三萜内酯化合物,命名为灵芝内酯(ganolactone)。根据光谱(UV,IR,¹HNMR,¹³CNMR,MS和2DNMR)解析,确定其结构为I式。同时还从赤芝子实体中分到三个已知化合物,即灵芝醇A(ganoderiolA,II),灵芝醇B(ganoderiolB,II)和灵芝三醇(ganodermatriolIV)。

Abstract: Four compounds were isolated from CH₂Cl₂ soluble fraction of the fruiting body of Ganoderma lucidum.On the basis of their spectral data( MS,UV,IR,¹HNMR,¹³CNMR and2DNMR)they were identified as 7β-hydroxy-3,11 ,15-trioxo-lanosta-8-en 24→20 lactone(Ⅰ),5α-lancota-7,9(11), dien-3β,24 ,25,26 tetrol(Ⅱ), 5α-lanosta-7,9(11),24-trien-3β.26-diol(Ⅲ)and 5α-lancota7,9(11),24-trien-3β,26,27-triol.Compound I is a new compound namedganolactone.