Abstract: In continuation of our studies on the leaves of Panax japonicus vat. major (Burk.) Wu et Feng, two new dammarane saponins are isolated.By means of FAB-MS and ¹³CNMR, their structures were elucidated as dammar-22(23)-ene-3β,6α, 12β,20(S) ,24§-pentaol- (20-O-β-D-glucopyranosyl)-6-O-α-L-rhamnopyranosyl(1-2)-β-D-glucopyranoside (majorosids F₅) and dammar-23(24)-ene-3β ,6α, 12β,20(S),25-pentaol-(20-O-β-D-glucopyranosyl)-6-O-α-L-rhamnopyranosyl(1-2)-β-D-glucopyranoside (majoroside F₆).