刘军保, 车锡平. 碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用J. 药学学报, 1984, 19(10): 790-791.
引用本文: 刘军保, 车锡平. 碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用J. 药学学报, 1984, 19(10): 790-791.
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LIU Jun-Bao, CHE Xi-Ping. EFFECTS OF DIMETHYL TRILOBINE IODIDE(DTI) ON BLOOD PRESSURE OF UNANESTHETIZED AND ACUTE RENAL HYPERTENSIVE RATSJ. Acta Pharmaceutica Sinica, 1984, 19(10): 790-791.
Citation: LIU Jun-Bao, CHE Xi-Ping. EFFECTS OF DIMETHYL TRILOBINE IODIDE(DTI) ON BLOOD PRESSURE OF UNANESTHETIZED AND ACUTE RENAL HYPERTENSIVE RATSJ. Acta Pharmaceutica Sinica, 1984, 19(10): 790-791.
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碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用

EFFECTS OF DIMETHYL TRILOBINE IODIDE(DTI) ON BLOOD PRESSURE OF UNANESTHETIZED AND ACUTE RENAL HYPERTENSIVE RATS

    摘要
  • Abstract: In acute renal hypertensive rats, the blood pressure could be reduced from 148.8±7.9 mmHg to 123.6±9.3 mmHg by intravenous injection of dimethyl trilobine iodide (DTI) at the dosage of 0.5 mg/kg. The hypotensive effect persisted more than 40 minutes.DTI also lowered the blood pressure of unanesthetized rats by feeding 3～10 mg/kg daily for 28 days, but it did not affect the SGPT of rats.

     

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