无纹紫背苔化学成分的研究

CHEMICAL STUDIES ON THE CONSTITUENTS OF PLAGIOCHASM INTERMEDIUM L.

摘要: 目的　研究苔纲植物无纹紫背苔（Plagiochasm intermedium L.）的化学成分。方法　用95%的EtOH回流提取，所得浸膏分部萃取后经硅胶柱及Sephadex LH-20柱色谱反复分离纯化，并用1DNMR，2DNMR及X-ray单晶衍射等技术对化合物的结构进行鉴定。结果　从无纹紫背苔中分离到6个化合物，分别鉴定为：双联苄类化合物Pakyonol（I）, 24-乙基胆甾-5,22-二烯-3β-软脂酸脂（24-ethylcholesta-5,22-dien-3β-ol-palmitic acid ester，II）, 22-羟基何伯烷（22-hopanol，III）, β-谷甾醇（β-sitosterol， IV），胡萝卜苷（daucosterol，V），甘露醇（mannitol，VI）。结论　II为新化合物, 其余化合物为首次从该属植物中分离得到。

Abstract: AIM　To study the chemical constituents of Plagiochasm intermedium L. METHODS　The plants were extracted with 95% EtOH and then separated by repeated silica gel and Sephadex LH-20 chromatographies. The structures of compounds isolated were identified by measurement of 1DNMR, 2DNMR spectrometry and X-ray crystallographic analysis. RESULTS　Six compounds were isolated. They were elucidated as pakyonol (I), 24-ethylcholesta-5,22-dien-3β-ol palmitic acid ester (II), 22-hopanol (III), β-sitosterol (IV), daucosterol (V), and mannitol (VI). CONCLUSION　Compound II is a new compound.