朱一婧 姜凤超. 以调控Ras信号传导为靶标的抗肿瘤药物研究进展J. 药学学报, 2009,44(1): 1-10.
引用本文: 朱一婧 姜凤超. 以调控Ras信号传导为靶标的抗肿瘤药物研究进展J. 药学学报, 2009,44(1): 1-10.
shu
SHU Yi-Jing, Jiang-Feng-Chao. Progress in the study of antitumor drug targeting on the Ras signaling pathwayJ. 药学学报, 2009,44(1): 1-10.
Citation: SHU Yi-Jing, Jiang-Feng-Chao. Progress in the study of antitumor drug targeting on the Ras signaling pathwayJ. 药学学报, 2009,44(1): 1-10.
shu

以调控Ras信号传导为靶标的抗肿瘤药物研究进展

Progress in the study of antitumor drug targeting on the Ras signaling pathway

    摘要
  • 摘要: Ras信号转导途径与肿瘤发生和生长密切相关, 针对此信号通路重要靶点的药物设计是当前抗肿瘤药物研究的热点。本文综述了Ras蛋白及与其上下游信号转导途径相关的靶点及其抑制剂的研究现状, 为新型抗肿瘤药物的研究设计提供参考依据。

     

    Abstract:

    Ras signaling pathway is closely related to the formation and growth of tumor. Currently, targeting on this signaling pathway is a hot research point for the design and development of anticancer drugs. In this paper, Ras protein as well as its related targets and inhibitors in signaling pathway were reviewed. It is expected to give research-related reference materials for the design of new anticancer drugs.

     

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