云南羌活的苷类成分

GLUCOSIDES FROM PLEUROSPERMUM RIVULORUM

摘要: 目的　研究云南羌活的化学成分。方法　用现代各种色谱方法分离云南羌活化学成分,用波谱技术(IR ,UV ,MS ,1D和2D-NMR)鉴定结构。结果　从云南羌活中分离得到4个苷类成分,分别鉴定为marmesinin (I) ,tert-O-β-D-glucopyranosyl heraclenol (II) ,1′-O-β-D-glucopyranosyl (2R ,3S)-3-hydroxynodakenetin (III)和8-hydroxy-5-O-β-D-glucopyranosyl psoralen (IV)。结论　III,IV为新化合物,所得4个苷类成分均为首次从该植物中分离

Abstract: AIM To study the chemical constituents of Pleurospermum rivulorum. METHODS To separate the constituents of P.rivulorum by using various kinds of chromatography and identify their structures on the basis of spectral analysis. RESULTS Four glucosides were isolated from P.rivulorum. Their structures were established as marmesinin (I), tert-O-β-D-glucopyranosyl-heraclenol (II), 1′-O-β-D-glucopyranosyl (2R,3S)-3-hydroxynodakenetin (III) and 8-hydroxy-5-O-β-D-glucopyranosyl-psoralen (IV) based on the analysis of spectral data of IR, UV, MS, 1D and 2D-NMR. CONCLUSION Compounds III and IV are new compounds. All of the four compounds were isolated from this plant for the first time.