金阳乌头生物碱的研究

陈迪华, 宋维良. 金阳乌头生物碱的研究J. 药学学报, 1981, 16(10): 748-751.

引用本文:

陈迪华, 宋维良. 金阳乌头生物碱的研究J. 药学学报, 1981, 16(10): 748-751.

Chen Dihua, Song Weiliang (W L Sung). STUDY ON ALKALOIDS OF ACONITUM JINYANGENSE W T WANGJ. Acta Pharmaceutica Sinica, 1981, 16(10): 748-751.

Citation:

Chen Dihua, Song Weiliang (W L Sung). STUDY ON ALKALOIDS OF ACONITUM JINYANGENSE W T WANGJ. Acta Pharmaceutica Sinica, 1981, 16(10): 748-751.

STUDY ON ALKALOIDS OF ACONITUM JINYANGENSE W T WANG

摘要: 从金阳乌头根中分得四种生物碱:光翠雀碱(Ⅰ),14-乙酰新乌碱(Ⅱ),金乌碱(Ⅲ)(新的C₂₀二萜生物碱)和碱Ⅳ(结构待定)。药理试验显示Ⅰ对乌头碱引起的心率不齐有预防作用。

Abstract: Four alkaloids were isolated from a new Aconitum species A. jinyangense: denudatine, 14-acetylneoline, jynosine, a new base identified as 15-acetyldenudatine, and a base, C₂₂H₃₃NO₂, mp 198～200℃.Pharmacological tests of denudatine showed prophylactic inhibition of cardiac arrhythmia caused by aconitine in rats.

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