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    First-in-class small molecule drugs in 2020
    WANG Lei, YOU Qi-dong
    2021, 56(2):341-351. DOI:10.16438/j.0513-4870.2021-0063
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    Updated research progress of selective PPARγ modulators
    HUAN Yi, PENG Jun, PAN Xuan, LIU Zhan-zhu, SHEN Zhu-fang
    2021, 56(2):352-359. DOI:10.16438/j.0513-4870.2020-1022
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    Current status and future of drugs targeting platelets-tumor cells interactions
    LI Shan, CHEN Zi-hao, L� Ming, ZHU Yan
    2021, 56(2):360-367. DOI:10.16438/j.0513-4870.2020-1122
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    Research advances on the protective effects and mechanism of salvianolic acids against ischemic heart disease
    DAWUTI Awaguli, FANG Lian-hua, DU Guan-hua
    2021, 56(2):368-373. DOI:10.16438/j.0513-4870.2020-1277
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    Recent advancement in targeting the KRAS-G12C mutant for cancer therapy
    LI Xin, WANG Yi-jun, LIU Ping-yu
    2021, 56(2):374-382. DOI:10.16438/j.0513-4870.2020-1485
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    Synaptic pruning mediated by glia in Alzheimer's disease
    LI Ling-jie, YU Xiao-lin, LIU Rui-tian
    2021, 56(2):383-390. DOI:10.16438/j.0513-4870.2020-1640
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    Role of gut microbiota in the treatment of ulcerative colitis with traditional Chinese medicine
    TAO Zhu-ping, LONG Yu, LI Can-wei, YIN Ai-wu, FAN Meng-ran, LI Ying, LIU Wei-hong, GAO Peng-fei
    2021, 56(2):391-402. DOI:10.16438/j.0513-4870.2020-1802
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    Research progress in multi-targeted anti-tumor natural products
    DUAN Yu-ting, MENG Ling-hua
    2021, 56(2):403-413. DOI:10.16438/j.0513-4870.2020-1224
    Abstract PDF
    Research progress on small molecule kinase inhibitors
    LONG Chun-ting, SHAO Min, LU Xiao-yun
    2021, 56(2):414-431. DOI:10.16438/j.0513-4870.2020-1027
    Abstract PDF
    Lead compound optimization strategy (8) drug transporters and related drug design strategies
    SONG Xiao-han, WANG Jiang, LIU Hong
    2021, 56(2):432-444. DOI:10.16438/j.0513-4870.2020-1248
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    Advances in the optimization of the linker in proteolysis-targeting chimeras (PROTAC)
    SHENG Xin-yuan, WU Shi-hui, LI Bao-lin, LI Xu-nuo, WU Hao-shu, CAO Ji
    2021, 56(2):445-455. DOI:10.16438/j.0513-4870.2020-1272
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    Identification and application of biomarkers in life cycle of drugs
    XIE Yuan-yuan, WANG Yi-ming, LUO Guo-an
    2021, 56(2):456-464. DOI:10.16438/j.0513-4870.2020-1374
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    Progress in tumor microenvironment responsive nano-platforms for cancer theranostics
    YANG Yu-qi, GONG Fei, BAI Shang, CHENG Liang
    2021, 56(2):465-475. DOI:10.16438/j.0513-4870.2020-1223
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    Research progress on metabolism and efficacy of small molecular prodrug nanosystems responsive to tumor redox microenvironment
    ZHAO Yao, YANG Can-yu, ZHANG Qiang, WANG Xue-qing
    2021, 56(2):476-486. DOI:10.16438/j.0513-4870.2020-1234
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    Research advances in the effect and utilization of protein corona on the circulation of nanoparticles in vivo
    ZHOU Dong-yan, JIANG Cheng, GUAN Zhi-yu, ZHU Wei-feng, ZHONG Ling-yun, LIU Jing, LIU Rong-hua
    2021, 56(2):487-495. DOI:10.16438/j.0513-4870.2020-1323
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    Preparation and anti-tumor activity of a novel antibody-drug conjugate 607-LDM
    YU Qun, YUAN Jia-lu, ZHAI Xiao-tian, MA Jian, MIAO Qing-fang, ZHEN Yong-su
    2021, 56(2):496-502. DOI:10.16438/j.0513-4870.2020-1225
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    Construction of a drug screening model for miscarriage from induced pluripotent stem cells in vitro
    WU Shan-shan, FAN Wen-juan, LI Rui-ling, WANG Yan-li, LI Pei-quan, LI Chao-jie, DENG Jin-bo
    2021, 56(2):503-510. DOI:10.16438/j.0513-4870.2020-1508
    Abstract PDF
    Rutaecarpine exerted anti-osteroporosis
    LI Yi-ning, HAN Xiao-wan, WANG Wei-zhi, JIANG Xin-hai, HAN Jiang-xue, ZHANG Jing, LI Ni, LI Dong-sheng, SHENG Ren, WU Ye-xiang, XU Yang, REN Yu, XU Yan-ni, SI Shu-yi
    2021, 56(2):511-519. DOI:10.16438/j.0513-4870.2020-1616
    Abstract PDF
    Bruceantin inhibits proliferation, migration and invasion of non-small cell lung cancer H1299 cells by up-regulating miR-29a-3p
    YAN Yan-yan, GUO Qiao-ru, FAN Xin-yue, ZHU Zhuang-yan, ZHANG Hai-yan, ZHOU Wen-min, YANG Lu-ming, HUANG Dong-yu, ZHANG Jian-ye
    2021, 56(2):520-527. DOI:10.16438/j.0513-4870.2020-1620
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    Metabolic module identification and biological mechanism of Xiaoyaosan for treatment of depression
    GAO Yao, MU Jun-fang, LING-HU Ting, ZHOU Yu-zhi, GAO Xiao-xia, TIAN Jun-sheng, QIN Xue-mei
    2021, 56(2):528-537. DOI:10.16438/j.0513-4870.2020-1079
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    Pharmacokinetic/pharmacodynamic modeling of the antitumor action of bispecific CD3/EpCAM antibody M701 in human colorectal cancer xenograft mice
    SONG Ling, YAO Qing-yu, XUE Jun-sheng, LI Si, ZHANG Jing, LIU Dong-yang, ZHOU Tian-yan
    2021, 56(2):538-544. DOI:10.16438/j.0513-4870.2020-0741
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    Identification of small molecule sirtuin-1 inhibitors for treating acute myeloid leukemia based on molecular docking, quantitative structure-activity relationships and molecular dynamics
    LIU Hong, ZENG Ming-hui, HE Jun, OUYANG Liang
    2021, 56(2):545-552. DOI:10.16438/j.0513-4870.2020-1461
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    A new dimeric benzylisoquinoline alkaloid from Corydalis yanhusuo
    XIA Gui-yang, XIAO Biao-bing, WANG Ling-yan, FANG Dong-jie, XIA Huan, LIN Sheng
    2021, 56(2):553-556. DOI:10.16438/j.0513-4870.2020-1564
    Abstract PDF
    Simultaneous quantitative analyses of six components in Astragalus membranaceus based on HPLC-CAD and quantitative analysis of multi-components with a single-marker
    YAO Jing, SUN Xin-guang, DONG Rong, XIE Jian-hong, WANG Yu-long, YANG Xiao-ning
    2021, 56(2):557-564. DOI:10.16438/j.0513-4870.2020-1430
    Abstract PDF
    Value assignment study on bioactivity of monoclonal antibody working reference standard
    YU Chuan-fei, LIU Chun-yu, WANG Lan
    2021, 56(2):565-569. DOI:10.16438/j.0513-4870.2020-1437
    Abstract PDF
    Preparation, characterization and improved solubility of ticagrelor salts
    YU Hong-mei, FANG Zheng-yu, XING Cheng, HU Kun, GONG Ning-bo, L� Yang
    2021, 56(2):570-576. DOI:10.16438/j.0513-4870.2020-1470
    Abstract PDF
    Establishment of a cocrystal characterization method for sacubitril valsartan sodium
    XIONG Jing, XU De-zhong, XU Xin-yi, L� Yang, YANG Shi-ying, WANG Si-cen
    2021, 56(2):577-584. DOI:10.16438/j.0513-4870.2020-1811
    Abstract PDF
    Mechanistic study on the solubility enhancement of puerarin by coamorphous technology
    WU Xiu-juan, PANG Zun-ting, YANG Si-tong, YAN Meng-meng, GAO Yuan
    2021, 56(2):585-592. DOI:10.16438/j.0513-4870.2020-1261
    Abstract PDF
    Preparation and enhanced photodynamic therapy of supramolecular nanoparticles to overcome tumor hypoxia
    YANG Xue-han, LIN Jiao, ZHANG Xue-ting, XU Hang, ZHANG Jia-liang, SONG Hong-tao
    2021, 56(2):593-603. DOI:10.16438/j.0513-4870.2020-1295
    Abstract PDF
    Preparation and targeting capability of corona forming in human ovarian plasma
    WANG Ya-zhen, GONG Tao, LI Yuan, GAO Hui-le
    2021, 56(2):604-609. DOI:10.16438/j.0513-4870.2020-1854
    Abstract PDF
    Cloning and bioinformatic analysis of the 3-ketoacyl-CoA synthase gene in Coix lacryma-jobi L.
    WEI Xiao-yan, LI Yong, GUO Juan, WANG Ya-nan, HUANG Lu-qi
    2021, 56(2):610-617. DOI:10.16438/j.0513-4870.2020-1407
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    Complete plastid genomes of Bupleurum chinense DC. and B. boissieuanum H. Wolff, with comparative and phylogenetic analyses of medicinal Bupleurum species
    ZHANG Ming-ying, ZHANG Yu-qu, LI Yi-min, GAO Jing, SHEN Xia, YANG Xin-jie, YAN Yong-gang, WANG Chang-li, ZHANG Gang
    2021, 56(2):618-629. DOI:10.16438/j.0513-4870.2020-1419
    Abstract PDF
    Cloning and expression analysis of chalcone isomerase from Aquilaria sinensis
    DING Ning, HAI Yan, WANG Xiao-hui, TU Peng-fei, GAO Bo-wen, SHI She-po
    2021, 56(2):630-638. DOI:10.16438/j.0513-4870.2020-1588
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    2021, 56(2):639-642. DOI:10.16438/j.0513-4870.2017-0454
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