PENG Ling-fang, LU Li-he, YANG Li-guo, LU Xue-ping, CUI Tao, ZHU Zhao-yun. A new biflavone from Dysosma versipellisJ. Acta Pharmaceutica Sinica, 2016,51(8): 1281-1284. doi: 10.16438/j.0513-4870.2016-0062
Citation: PENG Ling-fang, LU Li-he, YANG Li-guo, LU Xue-ping, CUI Tao, ZHU Zhao-yun. A new biflavone from Dysosma versipellisJ. Acta Pharmaceutica Sinica, 2016,51(8): 1281-1284. doi: 10.16438/j.0513-4870.2016-0062

A new biflavone from Dysosma versipellis

  • This study was conducted to investigate the chemical constituents in the root of Dysosma versipellis (Hance) M. Cheng. The constituents were isolated by silica gel, lichroprep RP-C18 and pharmadex LH-20 column chromatography and the IR, MS, NMR, 2D-NMR spectroscopic analysis were employed for the structural elucidation. Ten compounds were isolated from the 95% ethanol extract of Dysosma versipellis, their structures were elucidated as dysoverine D (1), dysoverine F (2), dysoverine A (3), podoverine A (4), α-peltatin (5), rutin (6), kaempferol-3-O-β-D-glucopyranoside (7), quercetin-3-O-β-D-glucopyranoside (8), kaempferol (9) and quercetin (10). Compound 2 is a new compound, and compounds 1 and 3-6 were isolated from this plant fo r the first time.
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