ZHAO Dan, WU Tong-yu, GUAN Yong-qiang, GUO Xiong-fei, MA Guo-xu, ZHANG Jing, SHI Lei-ling. A new sesquiterpenoid from the roots of Stelleropsis tianschanicaJ. Acta Pharmaceutica Sinica, 2017,52(8): 1302-1305. doi: 10.16438/j.0513-4870.2017-0254
Citation: ZHAO Dan, WU Tong-yu, GUAN Yong-qiang, GUO Xiong-fei, MA Guo-xu, ZHANG Jing, SHI Lei-ling. A new sesquiterpenoid from the roots of Stelleropsis tianschanicaJ. Acta Pharmaceutica Sinica, 2017,52(8): 1302-1305. doi: 10.16438/j.0513-4870.2017-0254

A new sesquiterpenoid from the roots of Stelleropsis tianschanica

  • Three sesquiterpenoids were isolated from the dichloromethane extract of the roots of Stelleropsis tianschanica Pobed through a combination of various chromatographic approaches, including silica gel, Sephadex LH-20, reverse phase C18 and so on. On the basis of spectroscopic data analysis, they were identified as (+)-guaia-l(10),ll-dien-9-one-5α-hydroxy (1), 4β,5βH-guai-9,7(11)-dien-12,8-olide-1α,8α-diol (2), 4α,5βHguai-9,7(11)-dien-12,8-olide-1α,8α-diol (3). The compound 1 is a new sesquiterpenoid, and the compound 3 was isolated for the first time from the genus Stelleropsis.
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