JIAN Jing-yi, CHEN Hui-huang, HONG Qi-sheng, WANG L�-huan, ZHAO Yu-mei, LI Lei, ZHANG Ting-ting, ZHOU Hai-bo, JIANG Zheng-jin. Advances in chromatography-based methods for screening active compounds from natural productsJ. Acta Pharmaceutica Sinica, 2020,55(7): 1504-1510. doi: 10.16438/j.0513-4870.2020-0088
Citation: JIAN Jing-yi, CHEN Hui-huang, HONG Qi-sheng, WANG L�-huan, ZHAO Yu-mei, LI Lei, ZHANG Ting-ting, ZHOU Hai-bo, JIANG Zheng-jin. Advances in chromatography-based methods for screening active compounds from natural productsJ. Acta Pharmaceutica Sinica, 2020,55(7): 1504-1510. doi: 10.16438/j.0513-4870.2020-0088
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Advances in chromatography-based methods for screening active compounds from natural products

    Abstract
  • Natural products have been a major source of leading compounds in drug discovery. How to effectively screen active compounds from complex matrix remains an interesting topic. In this review, we comprehensively summarized advanced liquid chromatography based approaches in natural products screening, including pre-column, on-column and post-column screening methods. Their advantages, disadvantages and prospect are also discussed.
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