GUO Jie, ZHANG Zhi-peng, CHENG Mao-jun, LIU Jing, ZHOU Wei-xin, XIE Sai-sai. Application of dithiocarbamates and their derivatives in medicinal chemistryJ. Acta Pharmaceutica Sinica, 2020,55(10): 2330-2339. doi: 10.16438/j.0513-4870.2020-0588
Citation: GUO Jie, ZHANG Zhi-peng, CHENG Mao-jun, LIU Jing, ZHOU Wei-xin, XIE Sai-sai. Application of dithiocarbamates and their derivatives in medicinal chemistryJ. Acta Pharmaceutica Sinica, 2020,55(10): 2330-2339. doi: 10.16438/j.0513-4870.2020-0588

Application of dithiocarbamates and their derivatives in medicinal chemistry

  • Dithiocarbamates and their derivatives with unique molecular structures possess diverse biological activities, which have become the research focus in the chemical and pharmaceutical fields in recent years. Here, we will review the structures, synthesis as well as biological activities of dithiocarbamates and their derivatives in anti-oxidation, anti-virus, anti-bacterial, anti-tumor and anti-Alzheimer's disease, and make a prospect for their development in the future.
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